Order Levitra (Vardenafil) online without prescription.
Impotency or erectile dysfunction is a common problem among men. This article tries to help you answer your questions.
1. How is erection achieved? Penile erection occurs with the relaxation of smooth muscle in the corpus cavernosum and its associated arterioles.
2. So why do some men experience erectile dysfunction being experiences it? Well, during sexual stimulation, from nerve ends in the corpus cavernosum, nitric oxide is released, which activates the enzyme guanylate cyclase resulting in an increased level of cyclic guanosine monophosphate in the corpus cavernosum, thereby allowing increased inflow of blood into the penis. If there is not enough blood flowing into the penis, then erectile dysfunction occurs.
3. How does Levitra fix the problem? By inhibiting PDE5, the enzyme responsible for cGMP degradation in the corpus cavernosum, Vardenafil potently enhances the effect of endogenous nitric oxide, locally released in corpus cavernosum upon sexual stimulation. Levitra thus potentiates the natural response to sexual stimulation.
4. What are the usual recommended doses of Levitra? • 10 mg taken approximately 25 - 60 minutes before sexual activity is the usual starting dose. Vardenafil was shown to be effective when taken up to 4 - 5 hours before sexual activity in clinical trials. • 5 mg dose should not go above when used in combination with the potent cytochrome P-450 inhibitors, ketoconazole, itraconazole, indinavir and ritonavir. • 10 mg dose should be exceeded when used in combination with erythromycin • 20 mg is the maximum recommended dosage and to be taken once daily. • dose may be increased to 20 mg or decreased to 5 mg depending on efficacy and tolerability • suggested maximum dose frequency is once daily. Levitra can be taken with or even without food. For a natural response to treatment, sexual stimulation is required.